VRTX vs Ultragenyx: which stock is doing better?
VRTX and Ultragenyx are business rivals. Where they compete: ultra-rare/orphan genetic disease therapies; similar small-patient-population, high-price specialty drug market. Here is how the two stocks, and the businesses behind them, compare over the past year.
Updated Oct 9, 2026
RARE ahead
On Stox’s P3 score, which combines market beat, staying power and business growth, Ultragenyx rates 28 and VRTX 19. Over the past year VRTX is +21% and Ultragenyx −50%, against +16% for the S&P 500. Ultragenyx has grown revenue faster, +13% against +10%. VRTX swings less, about 2.6% on a typical day against 5.7%. By type, VRTX is a Hot Hand and Ultragenyx a Wallflower.
The past year
VRTX against RARE, each set to $100 a year ago. Select a measure in the table below to chart it for both.
VRTX and RARE side by side
Ahead marks the stronger reading on each line; for the typical day and the deepest fall it marks the steadier stock. Select a row with a chart to see both over the year.
| Measure | VRTX | RARE | Ahead |
|---|---|---|---|
P3 score Market beat, staying power and business growth combined | 19Weak | 28Weak | RARE |
Past year Share price change | +21% | −50% | VRTX |
Past 3 months Share price change | +6% | −53% | VRTX |
Past month Share price change | −1% | +7% | RARE |
Market beat Return against the market, past year | 75Strong | 3Weak | VRTX |
Staying power How steadily it has led, 52 weeks | 0Weak | 83Strong | RARE |
Business growth Revenue, margins and cash flow growth | 85Strong | 91Strong | RARE |
Money flow Buying against selling on volume, 60 days | 81Strong | 45Middling | VRTX |
Revenue growth Past four quarters against the year before | +10% | +13% | RARE |
Operating margin Operating profit as a share of revenue, past four quarters | 39% | -84% | VRTX |
Typical day Average daily move over the past year | 2.6% | 5.7% | VRTX, calmer |
Deepest fall From a high, past year | −15% | −65% | VRTX, held up |
Market value What the market values the company at | $129.5B | $1.5B | |
Type Its Stox Atlas type | Hot Hand | Wallflower | |
Group Stocks it moves with | Health care | Health care | Same group |
How to read this page
How it’s measured. Scores from Stox rank each stock against about 1,200 large US stocks and funds, where 100 is best; P3 combines market beat, staying power and business growth. Returns are share-price changes. The typical day is the average true range over 14 days as a share of the price, averaged over the past year.
Sources. Daily prices and company financial statements from Financial Modeling Prep; scores and curated rivals from Stox.
A higher score describes a stronger past year, not what comes next.
Rivals are chosen by the markets the two businesses compete in, not by sector labels.
For financial statements, valuation and news, see VRTX and RARE on Stox.
This page is information, not investment advice. About our data and methods ›